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Endoscopic Screening of Asymptomatic Patients for Helicobacter Pylori, Intestinal Metaplasia, and Barrett's Mucosa During Screening Colonoscopy

Recruitingn/aAges 30 Years - anyAllSigmund Freud PrivatUniversitat
NCT07346521 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to learn how common Helicobacter pylori (H. pylori) infection is in adults without stomach or upper gastrointestinal symptoms who are having a preventive screening colonoscopy. Endoscopic screening of the stomach is yet not acceptet as a standard screening procedure in Western countries. However, Helicobacter pylori infection is known to increase the risk of developing gastric cancer. This study will look at the prevalence of Helicobacter pylori infection in asymptomatic patients who have an additional gastroscopy during the same session as their screening colonoscopy. It will also record other early tissue changes or risk factors for stomach cancer, such as intestinal metaplasia and Barrett's mucosa. The main questions this study aims to answer are: * How often is Helicobacter pylori found in adults without upper gastrointestinal symptoms by u

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥ 30 years * Scheduled screening colonoscopy (either initial screening or surveillance following previously detected polyps) * Asymptomatic (no gastrointestinal symptoms) * Willingness and consent to undergo simultaneous gastroscopy with biopsy sampling * Written informed consent to participate in the study, including the use of histological findings and patient data for study analysis Exclusion Criteria: * Known Helicobacter pylori infection or previous treatment for H. pylori * Current or recent proton pump inhibitor (PPI) therapy (\< 4 weeks) * Pre-existing gastrointestinal diseases (e.g., chronic gastritis, ulcer, gastric carcinoma) * Immunosuppression or relevant underlying diseases * Refusal to undergo additional gastroscopy or biopsy
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What it tests

  • Not listed
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Where

1 site
Wiener Privatklinik (WPK)
Vienna, Austria
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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