Preventive Effect of a Dietary Supplement With Two Probiotic Limosilactobacillus Reuteri Strains on Excessive Crying and Colic in Healthy Newborns.

Inclusion Criteria: 1. Infant is born at the maternity ward of UZ Brussel with a gestational age of ≥37 weeks. 2. Infant is healthy at the time of pre-examination. 3. Infant is aged between 1 and 14 days old at the time of inclusion. 4. Legal guardian(s) are able and willing to follow the study instructions 5. Infant is suitable for participation in the study according to the investigator/ study personnel 6. Legal guardian(s) willing to refrain products containing probiotics for their infant, from baseline (visit 1) throughout the study period (visit 3). 7. Informed written consent given by parent / legal guardian Exclusion Criteria: 1. No legal guardian's command of any local language 2. Infant with a major congenital anomaly (i.e. anal atresia, trisomy 21) or suspicion of any chronic disorder or disease (i.e. Hirschsprung's disease, metabolic disorder) 3. Infant is suffering from congenital or acquired immunodeficiency 4. Infant is suffering from an infection at the time of pre-examination or previous 7 days 5. Infant is admitted post-partum to the neonatal intensive care unit 6. Infant is not suitable for participation in the study according to the study personnel´s opinion