Safety and Efficacy of Platelet-Rich Plasma Combined With Compound Betamethasone in Arthroscopic Surgery for Rotator Cuff Injury With Shoulder Adhesion: A Prospective, Multicenter, Randomized Controlled Trial

Inclusion Criteria: Age between 18 and 70 years. Clinical and MRI diagnosis of full-thickness rotator cuff tear. Presence of shoulder stiffness/adhesion defined as passive range of motion less than 100° in forward flexion and/or less than 10° in external rotation (or according to your specific definition). Scheduled for arthroscopic rotator cuff repair and capsular release. Willing and able to provide written informed consent. Willing to comply with all study procedures and follow-up visits. Exclusion Criteria : Massive, irreparable rotator cuff tear. Severe glenohumeral osteoarthritis (Grade III or IV according to Samilson-Prieto classification). History of shoulder infection, fracture, or previous surgery on the affected shoulder. Known allergy or contraindication to betamethasone, local anesthetics, or components of PRP preparation. Systemic inflammatory arthritis (e.g., rheumatoid arthritis). Coagulation disorders or use of anticoagulants that cannot be safely suspended perioperatively. Pregnancy or lactation. Participation in another clinical trial within the past 3 months. Any medical or psychiatric condition that, in the investigator's opinion, would compromise patient safety or compliance with the study protocol.