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Pentoxifylline in Patients With Ulcerative Colitis

RecruitingPhase 2Ages 18 Years - 70 YearsAllIhab Elsayed Hassan
NCT07349472 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Ulcerative colitis (UC) is a persistent, idiopathic form of inflammatory bowel disease (IBD) marked by uninterrupted inflammation of the colon's mucosal lining, usually starting at the rectum and progressing proximally in a continuous manner. It manifests clinically with recurrent episodes of abdominal pain, bloody diarrhea, urgency, tenesmus, and weight loss. The precise cause of UC is still unknown; however, it is thought to arise from a multifactorial interaction involving genetic susceptibility, immune system dysregulation, disturbances in gut microbiota composition, and various environmental factors.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥ 18 years * Both male and female will be included * Negative pregnancy test and effective contraception. * Mild and moderate UC patients Exclusion Criteria: * Breast feeding * Significant liver and kidney function abnormalities * Diabetic patients * Colorectal cancer patients * Patients with severe UC * Patients taking rectal or systemic steroids * Patients taking immunosuppressives or biological therapies * Addiction to alcohol and / or drugs * Known allergy to the studied medications
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What it tests

  • Mesalamine
  • Pentoxifylline
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Where

1 site
Fayoum University
Al Fayyum, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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