Observation of the Effect of Preoperative Use of Dexmedetomidine Hydrochloride Nasal Spray on Optimizing Awake Sedation During Breast-Conserving Surgery for Breast Cancer and Postoperative Awake Status

Inclusion Criteria: * Sign the informed consent for * The patients included in the study were women aged between 20 and 70. * ASA (American Society of Anesthesiologists) I-II. * BMI:18-26 Kg/m ² Exclusion Criteria: * Subjects deemed unsuitable for nasal spray administration by the researchers (such as those with severe rhinitis, nasal deformities, etc.); * Severe bradycardia (HR \< 50 beats/min), history of cardiac conduction block; * History of upper respiratory tract infection; * History of asthma; * History of allergy to DEX or local anesthetics; * Subjects who have taken anti-anxiety medication before the operation; * Subjects with a history of ischemic stroke or transient ischemic attack; * Subjects with poorly controlled blood pressure despite medication; * Subjects with a history of mental illness, cognitive impairment, or epilepsy; * Subjects with a history of pregnancy; * Subjects who have been taking sedatives or analgesics for a long time; * Subjects with a history of liver or kidney function impairment; * Subjects with a history of drug or alcohol abuse; * Other situations that the reviewers consider to be disqualifying based on the registration study, such as potential non-compliance with the clinical protocol.