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Comparison Between Two Instrumentation Techniques on Postoperative Pain and Level of Neuropeptides

RecruitingNAAges 18 Years - 50 YearsAllAlexandria University
NCT07357233 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

General aim: assessment of post operative pain and time of preparation with the execution of manual-less technique and conventional technique. Specific aim: correlation between post operative pain and release of Substance P and Calcitonin gene-related peptide.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Patients with symptomatic irreversible pulpitis and apical periodontitis in mandibular molars with closed apex.(17) 2. Healthy males and females (Category: American Society of Anesthesiologists class I). 3. Age of patients range from 18 to 50 years old. 4. Those who could understand the use of the numeric rating scale (NRS) for pain. 5. In cases where radiographs show no root resorption or abnormal anatomy. 6. Patients with good oral hygiene and free from periodontal diseases. Exclusion Criteria: 1. Allergy to anesthetics. 2. Pregnancy 3. Unrestorable teeth. 4. Patient on analgesics. 5. Prescence of root resorption or abnormal anatomy.
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What it tests

  • Manual-less
  • Conventional technique
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Where

1 site
Alexandria Faculty of Dentistry
Alexandria, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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