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Eye-Brain-Kidney in CKD

Recruitingn/aAges 18 Years - 70 YearsAllBeijing Friendship Hospital
NCT07358572 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to learn about the interaction between the eyes, brain, and kidneys in adult patients with Chronic Kidney Disease (CKD). The main question it aims to answer is: Do changes in the brain's network connectivity and the retina's blood vessels correlate with cognitive decline and kidney function in CKD patients? Participants with CKD who are already undergoing clinical care will complete cognitive tests and questionnaires, have non-invasive MRI scans of their brain and kidneys, and undergo non-invasive eye imaging (OCT/OCTA) of their retinas.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Aged 18-70 years. 2. Patients clinically diagnosed with CKD stages 1-5. 3. No contraindications for MRI examination (e.g., cardiac pacemaker, claustrophobia, cochlear implant, hearing aid, coronary stents implanted before 2015) and able to complete the MRI scan. Exclusion Criteria: 1. Patients with recent or prior cerebral hemorrhage or cerebral infarction. 2. History of epileptic seizures or psychiatric disorders. 3. Patients with claustrophobia. 4. Pregnant or lactating patients. 5. Presence of other central nervous system diseases (e.g., tumor, trauma). 6. Unstable angina, congestive heart failure (NYHA class III or IV), or acute myocardial infarction. 7. Any systemic or other diseases deemed unsuitable for clinical trial participation.
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What it tests

  • Not listed
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Where

1 site
Beijing Friendship Hospital, Capital Medical University
Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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