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Microneedling With Platelet Rich Plasma Versus Microneedling Alone For Gingival Depigmentation

RecruitingNAAges 18 Years - anyAllCairo University
NCT07359339 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

To evaluate the usage of microneedling with platelet rich plasma as a gingival depigmentation method in comparison to microneedling alone for pigment intensity reduction. Pre-operative preparation phase includes ultrasonic scaling and oral hygiene instructions for all patients. Eligible patients will be randomly allocated into two groups. Clinical photographs: Clinical photographs will be taken at baseline, 1 and 6 months postoperatively. Intervention Group (Group A): Microneedling will be done with application of Platelet Rich Plasma for depigmentation. Control Group (Group B): microneedling will be done alone for depigmentation.

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📋 Eligibility rules (as published)
Inclusion Criteria: * • Patients exhibiting melanin hyperpigmentation in the anterior region of the upper or lower gingiva. * Age ≥ 18 year old. * Patients should be free from any systemic diseases according to modified Cornell Medical index (Abramson 1966). * Non- smokers Exclusion Criteria: * • Fully edentulous patients. * Patients with endocrine disorders causing hyperpigmentation or drug induced gingival pigmentation. (Sreeja, Ramakrishnan et al. 2015) * Pregnant or lactating females.
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What it tests

  • Microneedling will be done with application of Platelet Rich Plasma for depigmentation.
  • Microneedling alone for Gingival Depigmentation.
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Where

3 sites
Cairo university
Cairo, Egypt
Faculity of Dentistry, Cairo university
Cairo, Egypt
Faculity of Dentistry, Cairo university
Cairo, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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