🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Personalized Pulsed Radiofrequency of the Greater Occipital Nerve for Medication Overuse Headache

RecruitingNAAges 18 Years - 65 YearsAllAnkara City Hospital Bilkent
NCT07360782 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

This study evaluates a novel treatment approach for medication overuse headache (MOH) using greater occipital nerve pulsed radiofrequency (GONPRF). Three treatment strategies are compared: Standard Treatment: Limitation of overused acute headache medications, lifestyle counseling, and continuation of existing preventive medications. Primary GONPRF: GONPRF administered in addition to standard treatment. Modified GONPRF: GONPRF administered as a second-line intervention in individuals who do not respond adequately to standard treatment alone. The study assesses whether GONPRF, when applied early or after an initial period of standard care, reduces monthly headache days more rapidly and effectively than standard treatment alone. Outcomes are evaluated over a 6-month follow-up period using headache diaries and scheduled clinical assessments. This is a randomized controlled trial design

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria * Age 18-65 years * Diagnosed with Medication Overuse Headache (MOH) according to ICHD-3 criteria * No laboratory evidence of bleeding or clotting disorders * No active infection * Not pregnant and no suspicion of pregnancy * No history of craniocervical surgery that may alter anatomical structures at the intervention site * Able to understand the study procedures, provide written informed consent, and comply with treatment Exclusion Criteria * Changes in preventive treatment for migraine and/or tension-type headache within the last 3 months * Severe systemic disease (e.g., uncontrolled diabetes, serious cardiovascular disease, malignancy) * Psychiatric disorders (including current antidepressant use or psychiatric follow-up) * History of alcohol or substance abuse * Pregnancy, breastfeeding, or plans for pregnancy in the next 12 months * Concurrent use of other prophylactic headache treatments
💊

What it tests

  • Greater Occipital Nerve Pulsed Radiofrequency
  • Standard care
📍

Where

1 site
Ankara Bilkent City Hospital
Ankara, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy