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Percutaneous Transcatheter Genicular Embolization in Osteoarthritis

RecruitingNAAges 40 Years - 80 YearsAllMasarykova Nemocnice v Usti nad Labem, Krajska Zd…
NCT07361198 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This clinical study investigates a minimally invasive treatment called percutaneous transcatheter embolization of knee arteries for patients with chronic knee pain caused by advanced knee osteoarthritis or persistent pain after total knee replacement. Osteoarthritis of the knee is a common degenerative condition that can lead to long-term pain, reduced mobility, and decreased quality of life, and some patients do not achieve sufficient relief with standard treatments. The study is based on the hypothesis that targeted embolization of small arteries supplying the inflamed tissues of the knee can safely reduce abnormal blood flow associated with inflammation, leading to pain relief and improved knee function. During the procedure, a thin catheter is guided through the blood vessels to the affected area of the knee, where a temporary embolic agent is administered to reduce pathological blo

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults aged 40 to 80 years * Clinical symptoms consistent with chronic knee pain * Radiographically confirmed knee osteoarthritis of Kellgren-Lawrence grade II-IV or persistent knee pain following total knee arthroplasty * Insufficient pain relief after standard conservative treatment (e.g., pharmacological therapy, physical therapy, or injections) * Ability to understand the study procedures and provide written informed consent \_ Willingness and ability to comply with the study procedures and follow-up schedule Exclusion Criteria: * Active local or systemic infection * Known coagulation disorders or ongoing anticoagulation that cannot be safely interrupted * Significant peripheral arterial disease affecting the lower limbs * Known allergy or contraindication to iodinated contrast agents * Severe renal impairment * History of fibromyalgia or other generalized chronic pain syndromes that may confound pain assessment * Pregnancy or breastfeeding
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What it tests

  • genicular artery embolisation
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Where

1 site
Masarykova nemocnice v Ústí nad Labem
Ústí nad Labem, Czechia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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