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Nifedipine and Enalapril vs Nifedipine and Labetalol for the Treatment of Postpartum Hypertension Study

RecruitingNAAges 18 Years - anyFemaleThe Cleveland Clinic
NCT07363343 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

To determine if nifedipine and enalapril will have better blood pressure control in the postpartum setting compared to nifedipine and labetalol.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Postpartum women aged 18 years or older * Clinical diagnosis of hypertensive disorder in pregnancy (gestational hypertension, chronic hypertension, preeclampsia with or without severe features) * Taking Nifedipine 60 mg every 12 hours for blood pressure control * Persistently elevated blood pressure at/above 140/90 mmHg in a 24-hour time period or have one or more severe range blood pressure at/above 160/110 mmHg requiring a second antihypertensive medication * English speaking Exclusion Criteria: * Taking ≥2 antihypertensive agents during pregnancy * Heart block * Heart rate \<60 or \>120 beats per minute * Heart failure * Creatinine \>1.5 mg/dL * Renal artery stenosis * Active connective tissue disease * Cerebrovascular accident * Failed treatment or contraindications to nifedipine, enalapril or labetalol
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What it tests

  • Nifedipine and Enalapril
  • Nifedipine and Labetalol
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Where

1 site
Cleveland Clinic
Cleveland, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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