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Inhalational Agents Versus Dexmedetomidine for Maintenance of General Anesthesia

RecruitingNAAges 39 Years - 99 YearsAllBakirkoy Dr. Sadi Konuk Research and Training Hos…
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In plain words

What the trial is, and whether it could suit you

The climate crisis and environmental pollution are escalating day by day, making the reduction of carbon footprints increasingly important both on an individual and industrial level. Inhalational anesthetic agents are widely used in daily anesthesia practice. However, some of these agents are released into the environment either unchanged or as metabolic by-products. It can take hundreds of years for these substances to be fully eliminated from nature. Therefore, there is a growing interest in identifying alternative anesthetic agents that are fully metabolized, do not produce waste, have a shorter duration of action, and pose less harm to ecosystems. Recent clinical studies have shown that dexmedetomidine, when administered intraoperatively via infusion without a loading dose and in combination with inhalational agents, provides more stable hemodynamics and results in a shorter postope

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria * Age ≥ 39 years * Classified as ASA physical status II-IV * Scheduled for elective endoscopic urological surgery (e.g., URS, TUR-B, PCNL, TUR-P) * Scheduled for postoperative follow-up in the Post-Anesthesia Care Unit (PACU) * Ability to provide written informed consent Exclusion Criteria * Requirement for conversion to open surgery during the perioperative period * Patients who decline to participate in the study * Presence of neuropsychiatric disorders (e.g., dementia, Parkinson's disease, epilepsy, or history of head trauma) * History of alcohol or substance abuse * Use of psychoactive medications * Inability to communicate adequately for any reason
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What it tests

  • Dexmedetomidine + Remifentanil
  • Desflurane + Remifentanil
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Where

1 site
Bakirkoy dr. Sadi Konuk
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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