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Liposomal vs Conventional Oral Iron After Sleeve Gastrectomy

RecruitingNAAges 18 Years - 65 YearsAllMedeni Şermet
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In plain words

What the trial is, and whether it could suit you

Low-dose liposomal iron (17-34 mg elemental/day) was compared with standard conventional oral iron (100-200mg elemental/day) in the treatment of iron deficiency anemia following sleeve gastrectomy. Liposomal iron provided superior hematological improvement and gastrointestinal tolerance.

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📋 Eligibility rules (as published)
Inclusion Criteria * Age between 18 and 65 years * History of laparoscopic sleeve gastrectomy performed at least 6 months prior to enrollment * Diagnosis of iron deficiency anemia, defined as: * Hemoglobin \<12 g/dL in women or \<13 g/dL in men, and * Serum ferritin \<30 ng/mL or transferrin saturation (TSAT) \<20% * Mild to moderate anemia (hemoglobin ≥9 g/dL) * Ability to take and swallow oral medications * Willingness to participate and provide written informed consent Exclusion Criteria * Active gastrointestinal disease (e.g., inflammatory bowel disease, peptic ulcer disease, or gastrointestinal bleeding) * Chronic kidney disease with estimated GFR \<30 mL/min/1.73 m² * Use of oral or parenteral iron, vitamin B12, or folate supplementation within the previous 3 months * Iron overload or hemochromatosis (serum ferritin \>300 ng/mL) * Known allergy or intolerance to iron preparations * Active malignancy * Pregnancy or breastfeeding * Known hemoglobinopathies (e.g., thalassemia, sickle cell disease) * Blood transfusion within the previous 1 month * Cognitive or psychiatric disorder interfering with study participation or protocol adherence
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What it tests

  • Liposomal Iron
  • conventional oral iron
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Where

1 site
Goztepe Prof.Dr. Suleyyman Yalçın City Hospital
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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