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Magic Angle Direction Imaging (MADI) ACL Study

Recruitingn/aAges 18 Years - 65 YearsAllImperial College London
NCT07366619 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study will be conducted to see if a new Magnetic Resonance Imaging (MRI) scanner could give additional information or help view the body in a different way. The new scanner may be useful to diagnose conditions affecting tissues such as ligaments, tendons and cartilage more accurately, potentially improving the quality of care by the NHS. To develop such protocols and to test the clinical capabilities of the scanner, it is necessary to evaluate the scans of healthy volunteers before recruiting patient participants. Conventional MRI scans are unable to detect the signal from tissues such as ligaments, tendons, cartilage and cortical bone, which contain highly aligned collagen fibres and the signal decays too quickly to be captured. These tissues appear black and are only seen because of the surrounding brighter tissues. If a bright region appears, it can be a sign of an injury or dis

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📋 Eligibility rules (as published)
Inclusion Criteria: * adults aged 18 - 65 years * selected for ligament repair surgery * ability to give informed consent, either written or e-consent * no contraindications to MRI * BMI ≤ 28 or thigh circumference less than 47 cm at approximately 7.5cm above the joint line Exclusion Criteria: * acutely unwell or frail patients in whom extension of scanning time may not be tolerated or may delay treatment * contraindications to MRI * participants who are too big to be able to fit in the prototype scanner * recent surgery to the affected joint * severe pain * pregnant and/or breastfeeding participants
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What it tests

  • Magnetic Resonance Imaging
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Where

2 sites
Imperial College London
London, United Kingdom
Imperial College NHS Trust, Department of Surgery and Cancer
London, United Kingdom
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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