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Zinc Supplementation and Infections in Older Medical Patients

RecruitingNAAges 65 Years - anyAllHerlev Hospital
NCT07367412 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn about the effect of zinc supplementation once daily for 12 months in older acute medical patients. The main question it aims to answer is: • Can daily zinc supplementation for 12 months increase Days Alive and Out of Hospital (DAOH)? Researchers will compare zinc supplementation to a control group, a group who do not receive zinc supplementation, to see if zinc supplementation can increase Days Alive and Out of Hospital, reduce antibiotic use, readmissions and mortality. Participants will take 22 mg zinc supplementation once daily for 12 months or not. The researchers will draw data on readmissions, antibiotic use and mortality during the 12 months follow-up period.

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📋 Eligibility rules (as published)
Inclusion Criteria: * All medical patients aged ≥ 65 years assessed at the Medical Emergency Department, Herlev Hospital Exclusion Criteria: * Self-supplementing with zinc at time of assessment (\> 10 mg zinc/day) * Terminal illness (life expectancy \< 6 months, estimated by Clinical Frailty Scale ≥8) * Patients receiving parenteral nutrition (partial or complete) * Patients treated with hemodialysis or peritoneal dialysis * Patients know with known severe dementia * Patients who do not understand Danish and patients with temporary civil person registration numbers (CPR)
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What it tests

  • Zinc (zinc sulphate)
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Where

2 sites
Department of Medicine
Herlev, Denmark
Department of Medicine, Copenhagen University Hospital - Herlev and Gentofte
Herlev, Denmark
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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