🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Active Oxygen Releasing Gel With Photodynamic Therapy in Treating Stage III Periodontitis

RecruitingNAAges 30 Years - 70 YearsAllAlexandria University
NCT07368699 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Periodontitis is a serious gum disease that can damage the tissues supporting the teeth. The standard treatment is scaling and root planing of the teeth and roots. However, in some patients, this treatment alone may not fully control inflammation and harmful bacteria. This study aims to evaluate whether adding an active oxygen-releasing gel, with or without photodynamic therapy, improves treatment outcomes in patients with stage III periodontitis. The oxygen-releasing gel is applied to the gums and releases oxygen, which may help reduce harmful bacteria. Photodynamic therapy uses a light source together with a special dye to target and destroy bacteria and improve gingival health. In this randomized clinical trial, 42 patients with stage III periodontitis will be divided into three groups. One group will receive standard scaling and root planing (SRP) plus the oxygen-releasing gel. A s

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with periodontal diagnosis of stage III periodontitis * Patients with residual periodontal pocket depth ≥4 mm ,CAL≥ 5mm with bone loss extending to middle third of root and beyond in radiography * Bleeding on probing at least four sites at base-line * Patients who didn't receive periodontal treatment for a minimum of 3 months prior to the examination. * Patients of both sexes aged ≥30 and ≤70 years Exclusion Criteria: * Smokers or those with any other harmful habits such as pipe or vape smoking * Patients with any systemic condition that will possibly affect the outcome of periodontal therapy i.e. (diabetic patients) * Patients who have received any local or systemic anti-inflammatory medications or antibiotics within the last 6 months * Pregnant or lactating women * Patients with parafunctional habits
💊

What it tests

  • Scaling and root planing, topical active oxygen-releasing gel, and photodynamic therapy using diode laser
  • Scaling and root planing and topical application of active oxygen-releasing gel
  • Scaling and root planing
📍

Where

1 site
Faculty of Dentistry, Alexandria University
Alexandria, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy