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Vagus Nerve Stimulation Effect in Frozen Shoulder Treatment

RecruitingNAAges 40 Years - 65 YearsAllIstanbul University - Cerrahpasa
NCT07368751 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn if the addition of transcutaneous vagus nerve stimulation (tVNS) to exercise is effective in improving pain, shoulder function, shoulder range of motion, and psychological factors in adults with frozen shoulder. The main questions this study aims to answer are: Does adding tVNS to exercise reduce shoulder pain ? Does adding tVNS to exercise improve shoulder function and shoulder range of motion? Does adding tVNS to exercise improve psychological factors ? Does adding tVNS to exercise improve patient satisfaction? Researchers will compare the effect of active tVNS added to exercise with sham-controlled tVNS added to exercise to determine whether adding tVNS provides additional benefits in the management of frozen shoulder. Participants will: Receive active tVNS plus exercise therapy or sham-controlled tVNS plus exercise therapy. Attend sup

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age between 40 and 65 years. * Less than 50% range of motion compared with the contralateral shoulder in at least one movement (external rotation, abduction, flexion, or internal rotation). * More than 25% loss of range of motion in at least two movement planes compared with the unaffected shoulder. * Increasing limitation of glenohumeral external and internal rotation during abduction from 45° to 90°. * Shoulder pain lasting at least 3 months during activities of daily living. Exclusion Criteria: * Passive joint range of motion within normal limits * External rotation range of motion \<30° * Radiographic evidence of glenohumeral arthritis * Presence of inflammatory joint disease * Previous treatment related to the current shoulder complaint (physiotherapy and rehabilitation, intra-articular injection, or surgery) * Pain intensity \<3 according to the Numerical Pain Rating Scale (NPRS) * Presence of neurological deficits, cardiac disease, neuropathic disorders, or pregnancy
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What it tests

  • Active tVNS plus exercises
  • Sham controlled tVNS plus exercises
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Where

1 site
Istanbul University-Cerrahpaşa
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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