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Environmental Reservoirs of Non-tuberculous Mycobacteria in Cystic Fibrosis Households

Recruitingn/aAges any - anyAllResearch Center Borstel
NCT07369414 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This multicenter, non-interventional case-control study investigates whether household environmental reservoirs, particularly water systems, are associated with non-tuberculous mycobacterial (NTM) infections in people with cystic fibrosis (CF). Environmental samples from the homes of CF patients with and without NTM infection will be analyzed and genetically compared with available clinical isolates, alongside assessment of environmental risk factors, to improve understanding of exposure pathways and inform future prevention strategies.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Confirmed diagnosis of cystic fibrosis (CF) * No age restriction (including minors with consent from legal guardians) * Written informed consent to participate in the study (or consent provided by a legal guardian for minors) * In the case of an NTM infection: diagnosis according to ATS/IDSA criteria and availability of a clinical NTM isolate Exclusion Criteria: * Lack of capacity to provide informed consent, refusal to participate, or withdrawal of informed consent
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What it tests

  • Multi-modal NTM diagnostic including PCR, WGS, culture
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Where

2 sites
National and WHO-Supranational Reference Center for Mycobacteria, Research Center Borstel, Leibniz Lung Center
Borstel, Germany
Klinik für Pneumologie, Universitätsklinikum Essen
Essen, Germany
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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