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Carotid Artery Corrected Flow Time and Respiratory Variation of Blood Flow Peak Velocity for Prediction of Hypotension After Induction of General Anaesthesia in Adult Patients With Chronic Liver Disease

Recruitingn/aAges 18 Years - anyAllAin Shams University
NCT07370103 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Baseline Measurements For the ultrasound parameters, it is the average of three readings In supine position . The investigators will continuously monitoring during induction and 10 minutes after. Hemodynamic Monitoring: * Heart rate from ECG * SpO2 * Etco2 * Blood pressure . invasive Blood pressure * The radial artery level is the site of continuous arterial pressure monitoring with an arterial catheter. * Ultrasound Measurements: The patient will be positioned in a supine position, with the right side of the neck completely exposed. The transverse part Of the main carotid artery beneath the thyroid cartilage will be precisely identified using ultrasound device (sonosite edge portablp.fojy usa)via a linear array probe (4-15 MHz), with the marker directed toward the patient's head. Thus, the sampling line will be positioned at the center of the carotid lumen, around 2 cm from the car

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📋 Eligibility rules (as published)
Inclusion Criteria: * • Adult patients (≥ 18 years) with a confirmed diagnosis of CLD (e.g., cirrhosis, non-alcoholic steatohepatitis) * scheduled for elective surgery under general anesthesia. * ASA 2,3,4 * ASA 4 patients will be included only if their baseline MAP is \>65 mmHg, as per the exclusion criteria Exclusion Criteria: * • Refusal to participate * Patients with known cardiac disease (e.g., severe valvular disease, congestive heart failure), * pre-existing severe hypotension (e.g., mean arterial pressure \<65 mmHg * emergency surgery * anatomical variations preventing adequate ultrasound visualization of the carotid artery. * Carotid artery stenosis. * Mean arterial pressure (MAP) \> 120 mmHg before anesthesia * any previous record of neck surgery or trauma. * acute renal injury. * oral angiotensin receptor blockers or angiotensin-converting enzyme inhibitors (ACEI) * lateral, prone, and lithotomy operations * body mass index (BMI) \> 30 kg/m2 or \< 15 kg/m2
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What it tests

  • Not listed
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Where

1 site
Ainshams University
Cairo, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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