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Velocity-Based Resistance Training in Kidney Transplant Recipients

RecruitingNAAges 18 Years - 50 YearsAllFundación Universitaria del Area Andina
NCT07370727 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This randomized controlled trial aims to evaluate the effects of velocity-based resistance training on renal function and metabolic health in kidney transplant recipients. Participants will be randomized into two groups performing resistance training at different execution velocities (maximal intended vs. submaximal controlled). The intervention will last 12 weeks and include multi-joint exercises (squat, bench press, military press). Primary outcomes include renal function (serum creatinine, eGFR, blood urea nitrogen, uric acid) and metabolic markers (HDL, triglycerides, glucose, waist circumference, blood pressure). Secondary outcomes include muscle strength, force-velocity profile, anthropometry, physical activity, fitness perception, and adherence to immunosuppressive medication.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Men and women aged 18 to 50 years. * Kidney transplant performed ≥12 months before enrollment. * Stable graft function in the previous 6 months (serum creatinine \< 1.5 mg/dL, no rejection episodes). * Written medical clearance from a nephrologist to perform moderate-to-vigorous physical activity. * Signed informed consent. Exclusion Criteria: * Active autoimmune disorders. * Recent coronary disease (≤6 months). * Severe musculoskeletal limitations incompatible with resistance training. * Diagnosis of diabetes mellitus (pre- or post-transplant). * Current active infection. * Use of immunosuppressive drugs with contraindications for exercise (e.g., mTOR inhibitors at baseline).
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What it tests

  • Velocity-Based Resistance Training - Submaximal Velocity Protocol
  • Velocity-Based Resistance Training - Maximal Velocity Protocol
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Where

1 site
Colombia
Bogotá, Colombia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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