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โ† Trials
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External Validation of VVI

Recruitingn/aAges 18 Years - anyAllUniversity of Thessaly
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In plain words

What the trial is, and whether it could suit you

Failure of liberation from mechanical ventilation increases days spent being mechanically ventilated, the length of stay and the morbidity of patients. Thus it is crucial that those patients who are ready to be liberated are accurately detected. In this study the investigators want to externally validate an index (the volume-velocity index, VVI) which in a preliminary study was found to predict with high accuracy the outcome of ventilator liberation. In this study, in patients who are deemed ready to undergo weaning by their treating physician the investigators will measure the excursion of the diaphragm, the principal respiratory muscle, the inspiratory time and the tidal volume and the volume breathed by the patient at each respiration in three phases: 1. during pressure support ventilation with 5/5, 2. during pressure support ventilation with 8/0, 3. during t-tube or pressure suppor

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Mechanically ventilated patients for more than 48h * First Spontaneous breathing trial * Deemed as ready to undergo weaning by the treating physician, according to published readiness criteria (DOI: 10.1183/09031936.00010206) Exclusion Criteria: * pregnant patients * preexisting diaphragmatic disease or injury * tracheostomy
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What it tests

  • Not listed
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Where

3 sites
General University Hospital of Larissa
Larissa, Greece
AHEPA - University General Hospital
Thessaloniki, Greece
General Hospital of Thessaloniki "G. Papanikolaou"
Thessaloniki, Greece
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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