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EIT-Guided Respiratory Physiotherapy for Prolonged Mechanical Ventilation (PMV)

RecruitingNAAges 18 Years - anyAllCapital Medical University
NCT07372794 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Patients with prolonged mechanical ventilation (PMV) frequently experience impaired ventilation distribution, respiratory muscle dysfunction, secretion retention, and delayed liberation from mechanical ventilation. Electrical impedance tomography (EIT) provides real-time bedside visualization of regional ventilation and enables individualized respiratory physiotherapy strategies. This multicenter randomized controlled trial aims to evaluate whether EIT-guided respiratory physiotherapy improves ventilator-free days at day 28 compared with conventional respiratory physiotherapy in adult patients with PMV. Respiratory physiotherapy consists of airway clearance, chest physiotherapy techniques, breathing pattern optimization, and therapeutic positioning. In the EIT-guided group, real-time EIT imaging is used to individualize physiotherapy strategies based on predefined ventilation distribut

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥ 18 years. * Invasive mechanical ventilation for ≥ 21 consecutive days. * Clinically stable and eligible for respiratory physiotherapy as determined by the treating team. * Expected to remain on invasive mechanical ventilation for at least 48 hours after enrollment. * Written informed consent obtained from the patient or legally authorized representative. Exclusion Criteria: * Contraindications to electrical impedance tomography . * Hemodynamic instability requiring high-dose vasoactive support. * Severe hypoxemia refractory to optimization. * Unstable fractures or other contraindications to mobilization or positioning. * Pregnancy. * Expected death within 48 hours.
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What it tests

  • EIT-Guided Respiratory Physiotherapy
  • Conventional Respiratory Physiotherapy
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Where

1 site
Beijing Rehabilitation Hospital Affiliated to Capital Medical University
Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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