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Effect of Daily Intake of Gazpacho on Semen Quality and Oxidative Stress

RecruitingNAAges 18 Years - 45 YearsMaleGinefiv
NCT07375238 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn whether drinking a daily serving of gazpacho can improve semen quality in men with reduced sperm quality. The study will also examine how this dietary intervention affects oxidative stress and whether it is well tolerated. The main questions this study aims to answer are: * Does daily consumption of gazpacho improve semen quality in men with altered semen parameters? * Does this dietary intervention affect levels of oxidative stress in semen? * Is daily gazpacho intake feasible and well tolerated as part of a Mediterranean diet? Researchers will compare a Mediterranean diet plus daily gazpacho intake with a Mediterranean diet alone to determine whether adding gazpacho provides additional benefits for male reproductive health. Participants will: * Follow a standardized Mediterranean diet for 12 weeks * Drink 330 mL of gazpacho every day or

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📋 Eligibility rules (as published)
Inclusion Criteria: * Men aged 18 to 45 years * Andrological profile including altered semen parameters such as oligozoospermia, asthenozoospermia and/or teratozoospermia (O±A±T) * No clinical indication for sperm DNA fragmentation testing or advanced sperm selection techniques * Willingness and ability to comply with the study protocol, including adherence to a standardized Mediterranean diet * Signed and dated written informed consent form Exclusion Criteria: * Use of antioxidant supplements during the three months prior to study start. * Active smokers or men who have stopped smoking within the last three months. * Diagnosis of azoospermia, leucocytospermia or necrozoospermia. * Presence of severe systemic diseases or chronic conditions that could interfere with semen quality or adherence to the study. * Known allergy or intolerance to any ingredient of the gazpacho used in the study. * Any medical, psychological or social condition that, in the investigator's judgement, could compromise the subject's ability to participate fully or comply with the protocol requirements. * Simultaneous participation in another clinical study.
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What it tests

  • Standardized Mediterranean Diet
  • Gazpacho
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Where

1 site
GINEFIV Madrid (IVIRMA Group)
Madrid, Spain
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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