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โ† Trials
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Will a Pre-therapy Exercise Intervention Improve the Outcomes of Patients With Advanced Oesophageal Cancer?

RecruitingNAAges any - anyAllUniversity of Surrey
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In plain words

What the trial is, and whether it could suit you

Background Regular exercise can significantly improve physical and mental health during cancer treatment and reduce the time needed in the hospital. Animal studies suggest that exercise training can also reduce the number of cancer cells. For example, exercise training in mice produces more immune cells in the tumour. These immune cells in the tumour contribute to the destruction and reduction of the size of the tumour and are a vital component of effective immunotherapy (cancer treatment that helps the immune system fight cancer). In humans, exercise training and the immune response in tumours are less understood. Only 1 study has investigated the effect of a single exercise session before surgical removal of the prostate in prostate cancer patients. As the benefits of exercise are gained from weeks/months of exercise, no effect on the immune cells in the tumours were found. The inve

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Adults with resectable oesophageal adenocarcinoma who are planned for neoadjuvant chemotherapy followed by surgery Exclusion Criteria: * Inability to carry out CPET or exercise due to underlying health conditions * pregnancy * \<18 years old
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What it tests

  • Low intensity exercise
  • High intensity exercise
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Where

1 site
University of Surrey
Guildford, United Kingdom
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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