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Dynamic Airway Resistance & ML: Guide Sputum Suction in Ventilated Patients

RecruitingNAAges 18 Years - 90 YearsAllAffiliated Hospital of Nantong University
NCT07375667 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Research has shown that timely suctioning not only improves survival rates but also enhances the quality of life in ventilator-dependent patients. However, clinical judgment on the optimal timing for suctioning currently relies primarily on physician experience, lacking scientific evidence \[10\]. Airway viscous resistance reflects the frictional resistance encountered by gas flow within the airways and is closely associated with airway patency. When airway secretions increase, viscous resistance undergoes dynamic changes. Therefore, analyzing these dynamic variations in viscous resistance derived from ventilator waveforms to determine the optimal suctioning timing and assess its clinical impact on the progression of pulmonary inflammation holds significant scientific value and offers new insights and methodologies for clinical practice.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Clinical diagnosis of Acute Respiratory Distress Syndrome (ARDS) * Clinical diagnosis of Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD) * Clinical diagnosis of Severe pneumonia Exclusion Criteria: * Clinical diagnosis of multiple organ failure; * Clinical diagnosis of multiple organ bleeding;
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What it tests

  • The dynamics of airway resistance
  • conventional suctioning
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Where

3 sites
The First Affiliated Hospital of Bengbu Medical University
Bengbu, China
Peking Union Medical College Hospital
Beijing, China
the Second Affiliated Hospital of Zhejiang University School of Medicine
Hangzhou, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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