AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

Transcranial Alternating Current Stimulation in Lewy Body Dementia

RecruitingNAAges 18 Years - anyAllIRCCS Centro San Giovanni di Dio Fatebenefratelli
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

The aim of the study is to evaluate the safety, feasibility, clinical and biological efficacy, and predictors of efficacy of an intervention consisting of transcranial alternating current stimulation (tACS) in patients with Lewy Body Dementia (DLB). In neurodegenerative diseases, like DLB, the process of neurodegeneration is accompanied by a significant alteration in oscillatory activity. tACS is a neurophysiological method of non-invasive modulation of the excitability of the central nervous system that uses a mild electrical current. Recent studies have demonstrated the safety and efficacy of this method in modulating the natural brain oscillation frequencies underlying multiple cognitive processes, such as verbal memory, perception, and working memory. Preliminary data show that single stimulation with occipital ฮฑ-tACS results in a significant improvement in visuospatial abilities a

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Male or female subjects aged over 18 at the time of signing the informed consent form; * Presence of a clinical diagnosis of Lewy body dementia according to clinical criteria (McKeith et al., 2017) Exclusion Criteria: * Age younger than that stated in the inclusion criteria; * Incapacity to understand; * Contraindications for tACS and TMS: patients with cardiac pacemakers and metal implants that are not compatible with electric or magnetic fields, history of epilepsy, current pregnancy (Safety questionnaire)
๐Ÿ’Š

What it tests

  • Transcranial Alternating Current Stimulation
  • Sham Transcranial Alternating Current Stimulation
๐Ÿ“

Where

2 sites
IRCCS Istituto Centro San Giovanni Di Dio - Fatebenefratelli Brescia
Brescia, Italy
Azienda Sanitaria Universitaria Giuliano Isontina di Trieste
Trieste, Italy
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy