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Combination Antibiotic Therapy for Staphylococcus Aureus Bacteremia

RecruitingPhase 4Ages 18 Years - anyAllIntermountain Health Care, Inc.
NCT07376889 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to see if, in selected patients with a serious bacterial infection of the bloodstream, treating the bacterial infection with a combination of antibiotics is more effective than treating the infection with a single antibiotic. Participants must have blood cultures which are positive for a certain type of bacteria.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥18 years * Alive and admitted to an Intermountain Health (IH) hospital acute care unit at enrollment * Initial positive blood culture with either methicillin-resistant Staphylococcus aureus (MRSA) or methicillin-susceptible Staphylococcus aureus (MSSA), collected: 1. on or during the index admission to an IH hospital, or 2. in an ambulatory setting (laboratory, clinic or emergency department) within 48 hours of the index admission, or 3. at a non-IH network hospital within 24 hours of subsequent transfer to an IH hospital Exclusion Criteria: * Patient requests that patient health data not be included in the analysis
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What it tests

  • Antibiotic Monotherapy (AM) for patients with methicillin-sensitive S. aureus bacteremia (MSSAB)
  • Antibiotic Monotherapy (AM) for patients with methicillin-resistant S. aureus bacteremia (MRSAB)
  • Combination Antibiotic Therapy (CAT) for patients with methicillin-sensitive S. aureus bacteremia (MSSAB)
  • Combination Antibiotic Therapy (CAT) for patients with methicillin-resistant S. aureus bacteremia (MRSAB)
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Where

13 sites
Platte Valley Hospital
Brighton, United States
Saint Joseph Hospital
Denver, United States
St. Mary's Regional Hospital
Grand Junction, United States
Good Samaritan Hospital
Lafayette, United States
Lutheran Medical Center
Wheat Ridge, United States
St. Vincent Regional Hospital
Billings, United States
St. James Hospital
Butte, United States
Holy Rosary Hospital
Miles City, United States

…and 5 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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