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Norepinephrine With Ephedrine Versus Norepinephrine Alone During Spinal Anesthesia for Cesarean Delivery

RecruitingPhase 4Ages 18 Years - 40 YearsFemaleCairo University
NCT07379710 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

We hypothesize that the addition of ephedrine to norepinephrine infusion could decrease the incidence of post spinal hypotension(PSH) in parturient undergoing C.S under spinal anesthesia and minimize the changes in heart rate

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📋 Eligibility rules (as published)
Inclusion Criteria: * ASA physical status II * Age: 18 to 40 years * Undergoing Elective Lower Segment Cesarean Section under Spinal Anesthesia. Exclusion Criteria: * Uncontrolled cardiac morbidities As reduction of ejection fraction\< 60%, History (within 3months) of myocardial infarction, cerebrovascular accident, transient ischemic attacks or coronary artery disease/stents * Poorly controlled Hypertensive disorders of pregnancy * Peripartum bleeding * Coagulation disorders * Baseline systolic blood pressure (SBP) \< 100 mmHg * Refusal of patients.
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What it tests

  • Ephedrine and Norepinephrine infusion
  • Norepinephrine infusion
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Where

1 site
Faculty of Medicine, Cairo University, Cairo
Cairo, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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