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Modern Technologies in Lower Respiratory Tract Infections in Children

Recruitingn/aAges 0 Days - 24 MonthsAllHelse Møre og Romsdal HF
NCT07381790 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Lower respiratory tract infections (LRTIs) are a significant cause of childhood morbidity and mortality globally, particularly in low-income countries. In Norway, LRTIs is a leading cause of hospitalization among infants, representing a great socioeconomic burden. Bronchiolitis, a viral infection, is the main representation of LRTIs in infants. It affects the small airways, causing breathing- and feeding difficulties. Today, treatment relies on subjective evaluations, lacking objective measures for assessment. This increases the risk of both under- and over treating patients. In the long term, bronchiolitis increases risk of asthma, but it is unknown who the high-risk patients for chronic lung disease are. Lung ultrasonography (LUS) has emerged as a promising tool for assessing bronchiolitis severity and progression of the disease. The investigators will explore its use to improve diag

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📋 Eligibility rules (as published)
Inclusion Criteria: * clinical diagnosis of lower respiratory tract infection * with tachypnea and/or * wheezing * Retractions * Respiratory difficulties Exclusion Criteria: * Severe Congenital heart disease (not ASD, small VSD, PDA) * Cystic fibrosis and PCD * Neuromuscular diseases and other diseases with reduced airway clearance * Severe malacia, diagnosed by bronchoscopy by time of T0. * Foreign body inhalation * Pneumothorax * Pleural effusion (with need of invasive interventions) * Bronchopulmonary dysplasia or GA \<32 weeks * Caretaker not able to communicate in Norwegian or English * Weight \<3 kg
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What it tests

  • lung ultrasound
  • Tidal-flow volume loops
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Where

2 sites
Aalesund Hospital
Ålesund, Norway
St. Olavs Hospital HF
Trondheim, Norway
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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