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Evaluating the Effectiveness of an Internet-based Therapy (iCARE) to Treat Symptoms of Postpartum Depression

RecruitingNAAges 18 Years - anyFemaleUniversity of Southern Denmark
NCT07384273 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Postpartum depression (PPD) is a common and serious condition affecting 9.5% of women in high-income countries, and around 8% in Denmark. It shares core features with major depression, including low mood, loss of interest, and impaired functioning. Untreated PPD can persist for months, negatively impacting maternal well-being, child development, and family dynamics. In Denmark, systematic screening using the Edinburgh Postnatal Depression Scale (EPDS) is standard practice, but access to PPD treatment varies widely across municipalities. Cognitive behavioral therapy (CBT) is the most effective psychological intervention for perinatal depression, yet limited availability and long wait times create barriers to access to care. Internet-based CBT (iCBT) offers a scalable, cost-effective alternative that can be delivered flexibly at home. Evidence supports the efficacy of self-guided iCBT for

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📋 Eligibility rules (as published)
Inclusion Criteria: * Given birth within 6 months * Edinburgh Postnatal Depression Scale (EPDS) score above 7 * ≥age 18 * Access to the internet Exclusion Criteria: * Do not understand Danish language, * Substance abuse or dependence * Alcohol abuse, defined by a weekly consumption of alcohol exceeding 10 units * A diagnosis of schizophrenia, other psychotic disorders or in immediate need of psychiatric treatment.
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What it tests

  • Internet-based therapy (iCARE) and treatment as usual
  • Treatment as usual (TAU)
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Where

1 site
Research Unit of Child and Adolescent Psychiatry, Department of Clinical Research, University of Southern Denmark
Odense, Denmark
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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