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Deceased Donor Kidney Storage at 10 Celsius Versus Conventional Storage

RecruitingNAAges 18 Years - anyAllVanderbilt University Medical Center
NCT07385651 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to test how storage temperature of deceased donor kidneys affects kidney function after transplant in adult patients receiving a kidney transplant. The main question it aims to answer is: • Do patients that receive a kidney transplant stored at 10 °C have improved post-transplant kidney function? Researchers will compare patients who receive kidneys stored at 10 °C versus kidneys stored at 4°C (on ice, i.e. conventional storage) to see if kidneys stored at 10 °C have improved function. Participants will: * Be made aware of and consent to receive a kidney transplant that had been stored at 10 °C * Have their urine collected 24 hours after surgery to be analyzed for research

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📋 Eligibility rules (as published)
Participant inclusion criteria 1\. All adult single organ kidney transplant candidates on the waiting list at Vanderbilt University Medical Center (VUMC) will be eligible for enrollment. Participant exclusion criteria 1. Kidney transplant candidates less than 18 years old 2. Kidney transplant candidates that decline consent 3. Transplant candidates listed for multi-organ transplant Deceased donor organ inclusion criteria: 1. Donation after brain death or donation after circulatory death kidney donors, whose health care proxy has consented for donation and the possibility of research 2. Deceased donor kidneys that have been allocated to VUMC as a primary match offer prior to organ procurement will be eligible Deceased donor organ exclusion criteria: 1. Donors whose health care proxy has declined consent for the possibility of research 2. Deceased donor kidneys that have been allocated to VUMC as a backup offer 3. Deceased donor kidneys that have been allocated to VUMC as a post procurement offer 4. Deceased donor kidneys that have already been placed on ice
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What it tests

  • 10˚C deceased donor kidney storage using Traferox XPort
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Where

1 site
Vanderbilt University Medical Center
Nashville, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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