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A Clinical Trial to Study the Effects on the Olfaction Capacity of an Individual Undergoing Skull Base Surgeries Using Cautery vs Scalpel .

RecruitingNAAges 18 Years - anyAllAll India Institute of Medical Sciences, Jodhpur
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In plain words

What the trial is, and whether it could suit you

Olfaction is a prominent entity that determines a person's quality of life. During human evolution, olfaction has played an essential role in determining safe food, assessing threats, and developing social relationships. Endoscopic endonasal surgeries are widely used today for the removal of brain tumors involving the pituitary and skull base. The minimal invasiveness, rapid recovery, better visualization, and lower occurrence of complication make endonasal endoscopic surgery an ideal approach for tumors involving the pituitary and midline skull base. However, the olfactory epithelium is at risk of injury during endoscopic skull base surgeries due to the orientation of the olfactory epithelium fibers.It has been found that the olfactory neuroepithelium extends from the cribriform plate superiorly to the septum for the superior-most 1 to 2 cm medially and onto the upper half of the superi

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: -Patients undergoing endoscopic endonasal skull base surgeries that require the raising of a nasoseptal flap Exclusion Criteria: * Patients with preoperative anosmia due to any cause. * Patients with a previous history of sino-nasal, pituitary, or skull base surgery. * Patients with a medical history of neurodegenerative diseases (for example, Alzheimer's disease or Parkinson's disease), chronic rhinosinusitis
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What it tests

  • Scalpel
  • Cautery
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Where

1 site
All India Institute Of Medical Sciences
Jodhpur, India
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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