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Superficial Vein Thrombosis of the Upper Limb in Bacteremia Associated With PICCline and Midline Catheters: Frequency and Clinical Consequences

RecruitingNAAges 18 Years - anyAllCentre Hospitalier Universitaire de Nice
NCT07388381 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The use of long-term peripheral venous catheters inserted in the upper limb (PICC lines and Midlines) has increased markedly over recent years. Catheter-related bacteremias and venous thromboses are the main complications associated with these catheters. These events may occur independently or simultaneously. In addition, venous thromboses may involve the superficial venous system (SVT) or the deep venous system (DVT). Current guidelines define septic thrombophlebitis as the association of a bacteremia and a DVT along the venous course of the catheter. This represents a severe complication of catheter-related bacteremia, leading to a modification in the duration of antibiotic therapy. However, SVTs associated with catheter-related bacteremias along the catheter pathway are not included in the definition of septic thrombophlebitis and are not addressed by specific recommendations. The

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥ 18 years * Hospitalization in a department of Nice University Hospital * Expected length of hospitalization ≥ 72 hours * Diagnosis of catheter-related bacteremia on PICCline or Midline. * Affiliation with a social security system * No objection to the study Exclusion Criteria: * Pregnant or breastfeeding women * Legal protection measures (patients under guardianship, trusteeship, or judicial protection) * Inability to remove the catheter * Doppler ultrasound showing DVT in the upper limb at selection. * Inability to perform the initial routine Doppler ultrasound * Withdrawal of the patient's consent
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What it tests

  • Follow-up for catheter-related bacteremia
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Where

1 site
CHU de NICE
Nice, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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