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ESPB vs SPSIP for Postoperative Analgesia After CABG

RecruitingNAAges 45 Years - 85 YearsAllKutahya Health Sciences University
NCT07388745 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This prospective, randomized, active-controlled, double-blind, parallel-group study compares the postoperative analgesic efficacy and safety of ultrasound-guided bilateral Erector Spinae Plane Block (ESPB) versus bilateral Serratus Posterior Superior Intercostal Plane Block (SPSIPB) in adult patients (45-85 years, ASA I-III) undergoing elective coronary artery bypass graft surgery. The primary outcome is postoperative pain intensity assessed by Numeric Rating Scale (NRS) at 2, 4, 8, 16, 24, and 48 hours after surgery. Secondary outcomes include intraoperative fentanyl/remifentanil consumption, postoperative morphine consumption, patient-controlled analgesia (PCA) demand/delivery parameters (if PCA is used), need for rescue analgesics, extubation and mobilization times, peak inspiratory flow measured by incentive spirometry at predefined time points, ICU and hospital length of stay, recov

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 45-85 years * Scheduled for elective coronary artery bypass graft (CABG) surgery * American Society of Anesthesiologists (ASA) I-II-III * Patients who provide written informed consent and agree to participate in the study Exclusion Criteria: * Emergency cases * ASA IV-V * Known allergy to local anesthetics * Coagulopathy (platelet count \<100,000/mm³, INR \>1.5, aPTT \>1.5× normal) * Infection at the block injection site * Pregnancy * Patients who do not provide written informed consent or decline to participate after being informed
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What it tests

  • Ultrasound-guided Erector Spinae Plane Block (ESPB)
  • Ultrasound-guided Serratus Posterior Superior Intercostal Plane Block (SPSIPB)
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Where

1 site
Kütahya Health Sciences University Hospital
Kütahya, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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