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Crown Removal in Non-Surgical Peri-Implantitis Therapy: A Randomized Trial

RecruitingNAAges 18 Years - anyAllG. d'Annunzio University
NCT07391202 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The aim of this single-blind, randomized controlled clinical trial is to evaluate whether removal of the prosthetic crown influences the clinical effectiveness of non-surgical mechanical therapy in implants affected by peri-implantitis. The study is designed to compare changes in several clinical and radiographic parameters between baseline and follow-up examinations at 3, 6, and 12 months. The primary outcome measure will be the mean peri-implant probing depth (PIPD). Secondary outcomes will include changes in gingival recession (REC), radiographic marginal bone level (MBL), modified bleeding index (mBI), and additional patient-related variables.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with at least one implant diagnosed with peri-implantitis (Berglundh et al., 2018); * Patients with a crown on the implant affected by peri-implantitis that is removable; * Patients who have not received non-surgical peri-implant therapy in the previous 6 months; * Patients who have not taken systemic antibiotic therapy in the previous 3 months. Exclusion Criteria: * Full-Mouth Plaque Score (FMPS) \> 30% at the time of non-surgical therapy; * Pregnant or breastfeeding women; * Relevant medical history, in the opinion of the examining clinician, that could affect the outcome of non-surgical peri-implant therapy; * Smoking patients consuming \> 10 cigarettes/day.
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What it tests

  • Non-Surgical Peri-Implant Therapy without Crown
  • Non-Surgical Peri-Implant Therapy with Crown
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Where

1 site
Dental Clinic, Department of Innovative Technologies in Medicine and Dentistry, 'G. D'Annunzio' University of Chieti-Pescara
Chieti, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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