Autogenous Tooth Transplantation With Instrumentally Simulated Open Apex and Platelet-Rich Fibrin

Inclusion Criteria: Autotransplantation will be performed in selected cases with favorable biological and functional prognosis, including: * Early loss of permanent teeth due to trauma, extensive caries, or agenesis. * Dental agenesis, particularly involving premolars or incisors, when a suitable donor tooth is available. * Replacement of non-restorable teeth (fractures or destructive caries). * Preservation of alveolar bone in growing patients where implant therapy is contraindicated. * Functional and aesthetic rehabilitation of anterior teeth in pediatric and adolescent patients. * Post-traumatic oral rehabilitation in young patients. * Good general and oral health. * Presence of a vital and intact periodontal ligament on the donor tooth. * Adequate recipient site dimensions and morphology, or surgically adaptable. * Absence of active infection at the recipient site. Donor Tooth Selection Criteria * Tooth extracted for orthodontic purposes. * Impacted or erupting third molars with compatible morphology. * Suitable supernumerary teeth. Exclusion Criteria: * Poor patient compliance. * Active infection at the recipient site. * Smoking of more than 15 cigarettes a day •. Untreated periodontal disease * Pregnancy or breastfeeding at date of inclusion * Acute infections