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Comparative Study: Fistula Rerouting vs. LIFT for High Perianal Fistula

RecruitingNAAges 20 Years - 65 YearsAllCairo University
NCT07399353 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to compare two different surgery methods for treating a complex type of anal fistula. This condition is an abnormal tunnel connecting the inside of the anus to the skin nearby. The main questions the study aims to answer are: Which surgery has a lower chance of the fistula coming back (recurrence)? Which surgery has a lower chance of causing problems with bowel control (incontinence) after healing? Researchers will compare two surgery groups: Group 1: Fistula Rerouting Technique - a two-step surgery that moves the fistula tract to a safer area before opening it. Group 2: LIFT Technique - a surgery that ties off and closes the fistula tract from between the anal muscles. Participants will be randomly assigned by a computer to one of these two surgery groups. This helps ensure the comparison between the two surgeries is fair. Participants in this s

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult patients (age 20-65 years) presenting with a high perianal fistula, defined as:Trans-sphincteric fistula tract traversing the upper two-thirds of the external anal sphincter, Or Extrasphincteric fistula. * Patients with recurrent perianal fistula. * Ability to provide informed consent. Exclusion Criteria: * Patients with preoperative fecal incontinence (as assessed by the Cleveland Clinic Fecal Incontinence Score). * Diagnosis of inflammatory bowel disease (e.g., Crohn's disease, ulcerative colitis). * Pregnant women. * Pediatric patients (age \< 20 years). * Patients with complex, branching fistula tracts. * Any contraindication to spinal/general anesthesia or surgery.
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What it tests

  • Fistula Rerouting Technique
  • Ligation of Intersphincteric Fistula Tract
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Where

1 site
Faculty of Medicine Cairo University
Cairo, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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