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TRIAD - Tracking Risk in Integrated Alzheimer's Diagnostics.

Recruitingn/aAges 50 Years - anyAllIstituti Clinici Scientifici Maugeri SpA
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In plain words

What the trial is, and whether it could suit you

The study is based on the hypothesis that the integration of biological, psychological, and social factors, according to the biopsychosocial paradigm, allows for more accurate identification of the different stages of the Alzheimer's continuum (AD), facilitating early diagnosis and effective management. It is also hypothesized that the experience of the caregiver is a key element, capable of influencing the patient's experience and clinical course, representing a potential early indicator of risk. Primary objectives are (PO.1) Jointly analyze biological, psychological, and social factors at different stages of the AD continuum to construct multidimensional clinical profiles and integrated risk models. (PO.2) Examine the influence of psychological and social variables on the quality of life of patients and caregivers at different stages of the disease. (PO.3) Investigate the relationsh

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria (patients): * Age โ‰ฅ 50 years. * Presence of a primary caregiver, i.e., a person who provides regular care and who can actively participate in the study. * Understanding of the research objectives and ability to provide informed consent. Inclusion Criteria (caregivers): * Be the primary caregiver, providing care for at least six months. * Age โ‰ฅ 18 years, to ensure the ability to understand and actively participate in the study. * Understanding of the research objectives and ability to provide informed consent. Exclusion Criteria (patients): * Age under 50. * History of previous or concomitant neurological disorders (e.g., severe cerebrovascular accidents, brain tumors, traumatic injuries affecting cognitive functions) and neurodegenerative disorders. * History of major psychiatric disorders (e.g., schizophrenia, severe bipolar disorder, untreated major depression), alcohol or substance abuse. * Medical conditions that may interfere with cognitive function (e.g., advanced renal or hepatic failure, severe respiratory disorders, untreated hypothyroidism, B12 deficiency). * Decompensated systemic diseases with clinical instability and significant organ failure. * Marked sensory limitations (hearing or vision) and/or language difficulties. * Participation in other experimental studies involving previous or current involvement in clinical trials of anti-amyloid drugs or experimental drug treatments for AD in the previous 6 months. Exclusion Criteria (caregivers): * Presence of severe active psychiatric disorders (e.g., untreated major depression, psychotic disorder, or schizophrenia). * Difficulty participating in interviews and assessments due to language barriers, cognitive deficits, or other personal limitations.
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What it tests

  • Not listed
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Where

1 site
ICS Maugeri Montescano Institute
Montescano, Italy
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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