🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

The Effects of Preemptive Multimodal Analgesic on Endodontic Pain Following Root Canal Therapy.

RecruitingEARLY Phase 1Ages 18 Years - anyAllChattogram International Dental College
NCT07400471 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

A clinical trial comparing preemptive multimodal analgesics with placebo in the management of immediate and chronic post-endodontic pain. The study utilizes statistical methods such as chi-squared, T-tests, and regression analysis, accounting for multiple outcomes with the Bonferroni adjustment. Duloxetine hydrochloride and pregabalin, both available in Bangladesh, are evaluated as experimental drugs, while placebos are used to assess psychological effects on pain. All participants receive standard interventional treatments, with acetaminophen provided as needed, and ethical considerations are addressed according to international guidelines.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: 1. Patient's aged 18 years more. 2. ASA physical status I-II. 3. Patient with the complain of pain originated from teeth and surrounding structure. 4. Preoperative pain severity is moderate to severe. 5. Patient can be able to make communication about their pain. 6. Patients give consent to attain this research. 7. Patients have others concomitant chronic pain. 8. Patients who will have non-surgical endodontic treatment. 9. Patients who will have non-surgical endodontic retreatment. 10. Patients who will have surgical endodontic treatment. Exclusion Criteria: 1. Patient would not like to attain in research. 2. Patients have any medical condition those are contra indication for study drug. 3. ASA physical status III, IV, V. 4. Patient already under treated any anti convulsent drug. 5. Patient participant in other clinical trials. 6. Lack of motivation or poor adharence to study protocols. 7. Patient with Pregnancy 8. Severe organ dysfunction 9. Patient have Hepatitis B, and other cross infection disease like (HIV) 10. Uncontrolled comorbidities that patient do not fit for endodontic treatment. 11. Severe cognitive impaired patients. 12. History of certain cancers or severe hematological issues.
💊

What it tests

  • Pregabalin- Acetaminophen
  • Duloxetine- Acetaminophen
📍

Where

1 site
Professor. Dr. Md. Abu Saeed Ibn Harun
Chittagong, Bangladesh
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy