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A Clinical Trial Evaluating Patients With Primary Vitreoretinal Lymphoma

RecruitingPhase 3Ages 21 Years - anyAllAldeyra Therapeutics, Inc.
NCT07402876 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

A prospective, randomized, double-masked, dosing-frequency-controlled, multicenter clinical trial evaluating the safety and activity of intravitreally injected ADX-2191 (methotrexate injection USP) in patients with primary vitreoretinal lymphoma

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. 21 years old or older; of any gender 2. Biopsy proven primary vitreoretinal lymphoma 3. Presence of lymphomatous vitreous cells at the Screening Visit and/or any eye that has been vitrectomized to confirm the diagnosis of primary vitreoretinal lymphoma 4. Willingness to participate in the clinical trial as evidenced by signing of an informed consent Exclusion Criteria: 1. Known allergy or hypersensitivity to methotrexate 2. Planned eye surgery during the clinical trial 3. Women of childbearing potential who are pregnant or lactating 4. Pre-existing ocular or non-ocular conditions or diseases that, in the opinion of the investigator, could interfere with the conduct or interpretation of the clinical trial 5. Use of systemic methotrexate within one week prior to treatment
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What it tests

  • ICM ADX-2191 injection
  • Monthly ADX-2191 injection
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Where

1 site
Bascom Palmer Eye Institute
Miami, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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