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Urethral Resistive Index (URI): A New Parameter for Diagnosing Urethral Obstruction

Recruitingn/aAges 18 Years - 80 YearsMaleAnkara City Hospital Bilkent
NCT07403786 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This prospective observational study aims to evaluate the diagnostic accuracy of a new, non-invasive uroflowmetry parameter called the Urethral Resistive Index (URI) for detecting urethral stricture in men. Currently, diagnosing urethral stricture often requires invasive procedures like surgery or pressure-flow studies. This research seeks to develop URI as a practical and painless screening tool that could reduce the need for such invasive interventions. Study Procedures: A total of 60 male participants (30 with suspected urethral stricture and 30 healthy volunteers) will be enrolled. Participants will undergo two standard, non-invasive uroflowmetry (voiding) tests. The first test is a routine natural voiding session. The second test involves a "forced voiding" (Valsalva maneuver) once the participant feels a sufficient urge to urinate again. The URI is then calculated by comparing th

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📋 Eligibility rules (as published)
Inclusion Criteria: * Male participants aged between 18 and 80 years. * For the Stricture Group: Patients scheduled for surgery (urethroplasty or internal urethrotomy) due to suspected urethral stricture, where the diagnosis is confirmed intraoperatively. * For the Control Group: Healthy male volunteers without any lower urinary tract symptoms. * Voluntary signing of the Informed Consent Form. Exclusion Criteria: * Voiding volume less than 150 mL. * Causes of obstruction other than stricture, such as Benign Prostatic Hyperplasia (BPH). * Diagnosis of neurogenic bladder dysfunction or a history of neurological disease affecting bladder function. * Presence of severe comorbidities.
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What it tests

  • Uroflowmetry with URI Calculation
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Where

1 site
Ankara Bilkent City Hospital
Ankara, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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