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Comparison of Tendon and Muscle-Tendon Semitendinosus Grafts After ACL Reconstruction

RecruitingNAAges 18 Years - 50 YearsAllUniversity Hospital Dubrava
NCT07404046 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Aim: Comparison of tendon to bone ingrowth in bone tunnels and intra-articular remodeling of the graft after anterior cruciate ligament surgery with a muscle-tendon graft and those with a tendon graft. Subjects and methods: It is a single-blind prospective randomized study that would include at least 40 patients with an anterior cruciate ligament rupture. Patients would be randomly divided into two groups of minimally 20 patients each. Patients in the first study group would undergo ACL reconstruction with a muscle-tendon graft, while patients in the control group would be treated with the standard method of ACL reconstruction with a tendon graft. Expected contribution to the field: The assumption is that the obtained results could enable a better understanding of the contribution of remaining muscle fibers on the tendon in anterior cruciate ligament reconstruction operations to the ten

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📋 Eligibility rules (as published)
Inclusion Criteria: * Clinically and radiologically confirmed anterior cruciate ligament (ACL) rupture. * Age between 18 and 50 years. * Intact posterior cruciate ligament and collateral ligaments. * Signed informed consent to participate in the study. * Patients meeting at least one indication for concomitant lateral tenodesis, including: age under 25 years, positive pivot-shift test, presence of Segond fracture, participation in sports with frequent changes of direction and rotational knee loads, or joint hypermobility (Beighton score ≥ 7). Exclusion Criteria: * Previous ACL reconstruction of the same knee. * Inability to use a graft prepared by quadruple folding of the semitendinosus tendon. * Graft diameter \< 7.5 mm. * MRI-confirmed unsuccessful meniscal healing after repair. * Acute joint infection or history of joint infection.
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What it tests

  • ACL reconstruction
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Where

1 site
University hospital Dubrava
Zagreb, Croatia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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