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Direct vs Standard SLT for Glaucoma: A Noninferiority Trial

RecruitingNAAges 18 Years - anyAllMedical University of South Carolina
NCT07408154 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study compares two FDA-approved laser treatments for glaucoma: Direct Selective Laser Trabeculoplasty (DSLT) and Selective Laser Trabeculoplasty (SLT). Both procedures aim to lower eye pressure and prevent vision loss. DSLT is a newer, non-contact technique that may improve comfort and efficiency. Participants will be randomly assigned to receive either DSLT or SLT and followed for 12 months to assess eye pressure, safety, and treatment outcomes.

Sign in to get the eligibility rules as simple questions to take to your doctor.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥18 years * Diagnosis of OAG (including exfoliative or pigmentary) or OHT * Gonioscopically open angle (visible scleral spur 360°) * Ability to consent and comply with follow-up Exclusion Criteria: * Angle-closure or secondary glaucomas * IOP \>35 mmHg despite therapy * Corneal pathology interfering with laser or IOP measurement * Recent ocular surgery (\<6 months) * Contraindications to study medications or procedures * Cognitive impairment preventing consent
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What it tests

  • Direct Selective laser Trabeculoplasty
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Where

1 site
MUSC
Charleston, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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