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Sensory Stimulation as a Driver of Diet-induced Thermogenesis

RecruitingNAAges 18 Years - 40 YearsAllUniversity Hospital, Basel, Switzerland
NCT07409025 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to assess the influence of sensory stimulation on diet-induced energy expenditure by way of a clinical cross-over trial in 24 healthy participants either receiving a meal bolus with (orally) and without sensory stimulation (nasogastric-tube).

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📋 Eligibility rules (as published)
Inclusion Criteria: * healthy volunteers of any gender * BMI between 18-25 kg/m2 * age between 18 and 40 years Exclusion Criteria: * concomitant medication except for prescription free analgetics (paracetamol, NSAIDs) and oral contraceptives * clinically significant concomitant disease states (e.g. renal failure, hepatic dysfunction, cardiovascular disease, diabetes mellitus), * allergy to local anaesthetic or any of the study meal ingredients * known or suspected non-compliance, drug or alcohol abuse * smoker / habitual tobacco use * habitual excessive alcohol consumption * inability to follow the procedures of the study * participation in another study with investigational drug within the 30 days preceding and during the present study * previous enrolment into the current study * enrolment of the investigator, his/her family members, employees and other dependent persons * uncontrolled hypo- or hyperthyroidism * pregnancy or lactation
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What it tests

  • sensory exposure
  • sensory deprivation
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Where

1 site
University Hospital Basel, Department of Endocrinology
Basel, Switzerland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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