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Palatal Wound Healing After Free Gingival Graft Surgery

RecruitingNAAges 18 Years - anyAllKahramanmaras Sutcu Imam University
NCT07409571 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This randomized controlled clinical trial aims to evaluate the effects of topical triamcinolone acetonide application on wound healing and patient-reported outcomes at the palatal donor site following free gingival graft (FGG) surgery. A total of 55 patients with mucogingival deficiencies requiring FGG will be randomly assigned to either a control group receiving a collagen membrane or a test group receiving topical triamcinolone acetonide at the donor site. All palatal donor areas will be protected with a periodontal dressing. Clinical assessments will be performed on postoperative days 3, 7, 14, and 30. Wound epithelialization will be evaluated using the hydrogen peroxide bubbling test, while wound healing and scar formation will be assessed using the Landry, Turnbull, and Howley index and the modified Manchester Scar Scale, respectively. Patient-centered outcomes, including postoperat

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults aged 18 years and older * Patients presenting with insufficient attached gingiva and/or gingival recession requiring free gingival graft surgery * Systemically healthy individuals (ASA I) * Full-mouth plaque score (FMPS) \< 15% and full-mouth bleeding score (FMBS) \< 15% at the time of surgery * Ability and willingness to provide written informed consent and comply with study procedures Exclusion Criteria: * Presence of systemic diseases that may affect wound healing (e.g., diabetes mellitus, immunological disorders) * Use of systemic corticosteroids, immunosuppressive drugs, or anti-inflammatory medications within the last 3 months * Current smokers or tobacco users * Pregnancy or lactation * History of periodontal surgery at the palatal donor site * Presence of active infection, ulceration, or pathological lesions at the palatal donor area * Known allergy or hypersensitivity to corticosteroids, collagen materials, or study-related medications
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What it tests

  • kollajen membran (Cytoplast™ RTMFOAM™, Osteogenics Biomedical Inc., Texas, ABD)
  • triamcinolone acetonide
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Where

1 site
Kahramanmaraş Sütçü İmam University
Kahramanmaraş, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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