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โ† Trials
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EVOO and Metabolic Liver Health in MASLD

RecruitingNAAges 18 Years - 65 YearsAllAzienda Ospedaliera Specializzata in Gastroenteroโ€ฆ
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In plain words

What the trial is, and whether it could suit you

MASLD is currently one of the most common chronic non-communicable diseases and the leading cause of liver-related mortality and morbidity, with a rising prevalence worldwide, especially in the presence of obesity, diabetes, and other cardio-metabolic risk factors. Lifestyle modification, particularly through the Mediterranean Diet, is the first-line intervention, and extra virgin olive oil is a key component thanks to its monounsaturated fatty acids and bioactive compounds with anti-inflammatory and antioxidant effects. Several studies indicate that extra virgin olive oil supplementation, especially within a Mediterranean Diet pattern, reduces hepatic steatosis, improves inflammation, oxidative stress, and glucose and lipid profiles, and may promote weight loss and reduction of fat mass, also through potential effects on the gut microbiota. EFSA recognizes protective effects with a dai

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Subjects with 20 โ‰ค BMI \< 30; * Age range between 18 and 65 years, both sexes; * Diagnosis of hepatic steatosis, made on the basis of recognized criteria (FibroScan \[CAP (controlled attenuation parameter) \> 288 dB/m\], FLI). Exclusion Criteria: * Subjects with BMI \< 20 and BMI \> 30. * Presence of any condition that may influence the occurrence of steatosis other than the conditions representing inclusion criteria. * Pregnancy or breastfeeding. * Severe medical conditions that may compromise participation in the trial. * Individuals following a special diet.
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What it tests

  • Oil Supplementation - 3 tablespoons of oil
  • 9 Tablespoons of Oil
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Where

1 site
UOS Data Science
Castellana Grotte, Italy
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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