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Benefits of a Renal Rehabilitation Program Adapted to Uremic Patients on Daily Hemodialysis at Low Dialysate Flow Rate.

RecruitingNAAges 18 Years - anyAllBrugmann University Hospital
NCT07413315 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The concept of renal rehabilitation has become increasingly important with the increasing age of patients with severe or even terminal chronic kidney disease (CKD). It combines physical exercise and nutritional monitoring programs for patients with terminal CKD who are most often treated with conventional hemodialysis (HD) at a rate of 3 sessions of 4 hours per week. Sarcopenia is a very common phenomenon in patients with CKD. The prevalence found in recent meta-analyses varies between 25.6 and 28.5% in patients treated with dialysis. It is even higher in patients treated with HD than in patients treated with peritoneal dialysis (PD). Younger and more active patients will more often choose PD. The conventional HD modality preserves residual renal function less well, which is important for better elimination of uremic toxins bound to plasma proteins. Conventional HD requires a higher imm

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📋 Eligibility rules (as published)
Inclusion Criteria: * patient with terminal chronic kidney disease requiring hemodialysis treatment * patient recently hospitalized for an acute medical event. Exclusion Criteria: * dementia/mild cognitive impairment (MMSE \< 20/30) * decompensated psychiatric pathology and/or behavioral disorders * pregnant woman * recovery of renal function allowing interruption of helodialysis sessions * candidate for neurological rehabilitation * patient with recent spinal cord injury * patient with absolute and/or relative contraindication to performing a stress test * severe or poorly tolerated cardiac rhythm disorder * severe or symptomatic obstruction to left ventricular ejection * decompensated heart failure * acute myocarditis, pericarditis or endocarditis * acute aortic dissection * high-risk emboligenic intracardiac thrombus * significant stenosis of the common trunk * ventricular aneurysm * supraventricular tachycardia with poorly controlled ventricular rate, acquired high-degree or complete block * obstructive cardiomyopathy with high resting gradient * recent stroke or TIA * acute venous thrombosis with or without pulmonary embolism * poorly controlled clinical condition, such as marked anemia, significant electrolyte disturbance, hyperthyroidism, etc. * lack of cooperation from the patient * Blood pressure \> 200/110 mmHg
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What it tests

  • Low flow rate hemodialysis
  • Multidisciplinary rehabilitation program
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Where

1 site
CHU Brugmann
Brussels, Belgium
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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