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High-Intensity Laser Therapy in Carpal Tunnel Syndrome: Clinical, Sonographic, and Electrophysiological Outcomes

RecruitingNAAges 18 Years - 65 YearsAllAnkara City Hospital Bilkent
NCT07414069 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy of the upper extremity and is characterized by pain, paresthesia, and functional impairment resulting from increased pressure within the carpal tunnel. Although conservative treatment approaches such as splinting and pharmacological therapy are commonly used, High-Intensity Laser Therapy (HILT) has emerged as a non-invasive modality with potential analgesic, anti-inflammatory, and biostimulatory effects. However, evidence regarding its efficacy remains limited, particularly from sham-controlled studies incorporating objective outcome measures. This prospective, randomized, double-blind, sham-controlled clinical trial aims to evaluate the clinical, sonographic, and electrophysiological effectiveness of HILT in patients with mild-to-moderate CTS. Eligible patients aged 18 to 65 years with electrophysiologically confirmed

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age between 18 and 65 years * Clinical symptoms consistent with carpal tunnel syndrome * Electrophysiologically confirmed mild or moderate carpal tunnel syndrome * Ability to comply with the study protocol and follow-up assessments * Provided written informed consent Exclusion Criteria: * Severe carpal tunnel syndrome on electrophysiological examination * Previous surgical treatment for carpal tunnel syndrome * Local causes of carpal tunnel syndrome (e.g., mass lesions, ganglion cysts, tumors) * Systemic conditions associated with carpal tunnel syndrome (e.g., diabetes mellitus, hypothyroidism, pregnancy, acromegaly) * History of corticosteroid injection for carpal tunnel syndrome within the last 6 months * Presence of polyneuropathy, radiculopathy, or other upper extremity peripheral nerve disorders * Contraindications to electrophysiological testing or laser therapy * Inability to complete follow-up assessments
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What it tests

  • High-Intensity Laser Therapy (HILT)
  • Sham High-Intensity Laser Therapy
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Where

1 site
Ankara Bilkent City Hospital
Ankara, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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