The AMPER Study: Evaluation of the Efficacy of Human Amniotic Membrane Grafting in Preventing Mesh Exposure in Vaginal Reconstructive Surgery Using Polypropylene Mesh.

Inclusion Criteria: * Pelvic organ prolapse (POP) stage II C or greater, defined as C ≥ +1, in women without prior hysterectomy and/or with a diagnosis of stress urinary incontinence seeking surgical treatment. * Ability to understand study information and provide written informed consent. * Availability for follow-up for a minimum of 12 months. Exclusion Criteria: * Previous surgery with synthetic mesh (via vaginal or abdominal approach) for POP repair. * Known adverse reaction to synthetic meshes. * Unresolved or active chronic pelvic pain. * History of prior abdominal or pelvic radiation. * Contraindication to the planned surgical procedure. * Current pregnancy.