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Comparison Between Water Vapor Thermal Therapy and Prostatic Artery Embolization in Treatment of Benign Prostatic Hyperplasia

RecruitingNAAges 50 Years - anyMaleAin Shams University
NCT07416227 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The aim of this study is to compare the effectiveness of Rezum therapy versus Prostatic Artery Embolization in managing moderate-to-severe lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH), with the primary endpoint being the improvement in the International Prostate Symptom Score (IPSS) over a 6-month follow-up period. Secondary endpoints include changes in post-void residual urine (PVR), maximum urinary flow rate (Qmax), patient-reported quality of life (QoL), and the preservation of ejaculatory and overall sexual function as assessed by validated questionnaires. This study aims to provide evidence-based guidance for optimizing treatment strategies for men with BPH, particularly those seeking alternatives to pharmacological therapy.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥50 years. * IPSS ≥13. * Prostate volume between 30-80 mL. * Maximum urinary flow rate (Qmax) ≤15 mL/sec in patients with voiding LUTs. * Patients not responding to medical treatment. Exclusion Criteria: * History or suspicion of prostate cancer. * Previous prostate surgery or minimally invasive BPH intervention. * Neurological bladder dysfunction. * Active urinary tract infection.
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What it tests

  • Rezum
  • Prostatic Artery Embolization
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Where

1 site
Ain Shams University
Cairo, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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